Plasma cannon

Plasma cannons are weapons which fire bursts of plasma at opponents.

Generation 1
Quake's primary weapon in tank mode is his turret-mounted plasma cannon with a range of 40 miles. His allies would be more impressed with it, if he wasn't just as likely to blow them up as a platoon of Autobots. Longtooth is armed with a hand-held plasma cannon.

Prime
Optimus Prime wields a plasma cannon, which is usually integrated into and can be deployed from his right arm.

War for Cybertron
The Plasma Cannon was a favored weapon of Scout and Cloaker class Transformers during the Great War. It released bolts that could be charged to higher intensity levels. The Plasma Cannon was most effective against big, slow-moving targets, like hovering Soldiers or Trypticon.