Istanbul

Istanbul, historically also known as Constantinople and Byzantium, is the most populous city in Turkey and the country's economic, cultural, and historic center. Istanbul is a transcontinental city in Eurasia, straddling the Bosphorus strait between the Sea of Marmara and the Black Sea. Its commercial and historical center lies on the European side and about a third of its population lives on the Asian side. The city is the administrative center of the Istanbul Metropolitan Municipality (coterminous with Istanbul Province), both hosting a population of around 14 million residents. Istanbul is one of the world's most populous cities and ranks as the world's 7th-largest city proper and the largest European city.

The Transformers cartoon
During his search for the Pearl of Bahoudin, Megatron rampaged across Istanbul, demanding to know the location of Abdul Ben Faisal, a notable sage. After finding him, Abdul decided that Istanbul had suffered enough and told the Decepticon leader where the Pearl was buried.

Later, Istanbul was marked as the final city in the Europa 2000, which the Decepticons set up to gain Auggie Cahnay's new car.